BINA

We present a fiber-based photonic computing concept and system which rely on incoherent data encoding and scalable architecture. Our results suggest projected performance of> 1,000,000 Tera operations per second (TOPs) and efficiency of> 1000 TOPs/Watt.

We demonstrate a high-fidelity directional coupler in photonic integrated waveguides, utilizing a novel scheme of detuning modulated composite segments. We reduce the wavelength dependence by almost an order of magnitude, indicating significantly increased robustness.

“However, this technique suffers from the fact that it requires a lot of image processing tools, and post processing”“Another interesting approach is to exploit the memory effect of speckles. Memory effect states that there exists a correlation between a speckle pattern even when the laser illumination is tilted within a given angular range. Freund12, 13 used the scattering media as a lens based on speckle intensity correlation. This idea was extended by Bertolotti et al. 14 to image a fluorescent object behind the media.” now reads:“Another interesting approach is to exploit the memory effect of speckles. Memory effect states that there exists a correlation between a speckle pattern even when the laser illumination is tilted within a given angular range. Freund12–14 used the scattering media as a lens based on speckle intensity correlation. This idea was extended by Bertolotti et al. 13 to image a fluorescent object behind …

Integrated, discrete time microwave filters are realized in surface acoustic wave photonic devices in standard silicon on insulator. The devices are scaled to 16 and 32 taps. A single 7 MHz-wide passband is demonstrated.

Nitrogen-vacancy (NV) center in diamond is a promising quantum sensor with remarkably versatile sensing capabilities. While scanning NV magnetometry is well-established, NV electrometry has been so far limited to bulk diamonds. Here we demonstrate imaging external alternating (AC) and direct (DC) electric fields with a single NV at the apex of a diamond scanning tip under ambient conditions. A strong electric field screening effect is observed at low frequencies due to charge noise on the surface. We quantitatively measure its frequency dependence, and overcome this screening by mechanically oscillating the tip for imaging DC fields. Our scanning NV electrometry achieved an AC E-field sensitivity of 26 mV/µm/√ Hz, a DC E-field gradient sensitivity of 2 V/µm2/√ Hz, and sub-100 nm resolution limited by the NV-sample distance. Our work represents an important step toward building a scanning-probe-based multimodal quantum sensing platform.

We demonstrate experimentally symmetry breaking in a linear cavity mode-locking laser due to a non-local Kerr-lens, which is expressed in deviation from the soliton model. The effect is backed by numerical simulation with quantitative agreement.

Terpene synthases are responsible for the biosynthesis of terpenes, the largest family of natural products. Hydropyrene synthase generates hydropyrene and hydropyrenol as its main products along with two byproducts, isoelisabethatriene A and B. Fascinatingly, a single active site mutation (M75L) diverts the product distribution towards isoelisabethatriene A and B. In the current work, we study the competing pathways leading to these products using quantum chemical calculations in the gas-phase. We show that there is a great thermodynamic preference for hydropyrene and hydropyrenol formation, and hence most likely in the synthesis of the isoelisabethatriene products kinetic control is at play.

Tailoring the precise construction of non‐precious metals and carbon‐based heterogeneous catalysts for electrochemical oxygen evolution reaction (OER) and methanol oxidation reaction (MOR) is crucial for energy conversion applications. Herein, this work reports the composite of Ni doped Fe2O3 (Ni−Fe2O3) with mildly oxidized multi‐walled CNT (O−CNT) as an outstanding Mott‐Schottky catalyst for OER and MOR. O−CNT acts as a co‐catalyst which effectively regulates the charge transfer in Ni−Fe2O3 and thus enhances the electrocatalytic performance. Ni−Fe2O3/O−CNT exhibits a low onset potential of 260 mV and overpotential 310 mV @ 10 mA cm−2 for oxygen evolution. Being a Mott‐Schottky catalyst, it achieves the higher flat band potential of −1.15 V with the carrier density of 0.173×1024 cm−3. Further, in presence of 1 M CH3OH, it delivers the MOR current density of 10 mA cm−2 at 1.46 V …

Photonic integrated circuits play a central role in current and future applications such as communications, sensing, ranging, and information processing. Photonic quantum computing will also likely require an integrated optics architecture for improved stability, scalability, and performance. Fault-tolerant quantum computing mandates very accurate and robust quantum gates. In this work, we demonstrate high-fidelity directional couplers for single-qubit gates in photonic integrated waveguides, utilizing a novel scheme of detuning-modulated composite segments. Specific designs for reduced sensitivity to wavelength variations and real-world geometrical fabrication errors in waveguides width and depth are presented. Enhanced wavelength tolerance is demonstrated experimentally. The concept shows great promise for scaling high fidelity gates as part of integrated quantum optics architectures.

In this work, we demonstrate optomechanical measurements of radiation induced alterations of the acoustic velocity in a fluoroacrylate polymer coating of a silica optical fiber. The optomechanical measurement is based on forward Brillouin scattering initiated in the fiber core which stimulates acoustic waves that reach the fiber coating. The measurement may serve as an additional metric to quantify the dose of ionizing radiation to which the fiber was exposed. We have demonstrated that the stiffness of the coating increases following gamma irradiation, as measured by the time of flight of radial acoustic waves through the coating. The measurement was performed on few meters long fiber, but can be extended to a spatially distributed analysis in longer fibers. The tests showed a linear dependence of the acoustic time-of flight on the overall dosage of gamma irradiation. The time of flight decreased by as much as 15 …

In the vicinity of a narrow Feshbach resonance Efimov features are expected to be characterized by the resonance's properties rather than the van der Waals length of the interatomic potential. Although this theoretical prediction is well established by now, it still lacks experimental confirmation. Here, we apply our recently developed three-channel model [Y. Yudkin and L. Khaykovich, Efimov scenario for overlapping narrow Feshbach resonances, Phys. Rev. A 103, 063303 (2021)] to the experimental result obtained in a mass-imbalanced Li 6− Cs 133 mixture in the vicinity of the narrowest resonance explored to date [J. Johansen, BJ DeSalvo, K. Patel, and C. Chin, Testing universality of Efimov physics across broad and narrow Feshbach resonances, Nat. Phys. 13, 731 (2017)]. Our analysis suggests that the observed position of the Efimov resonance is dictated mainly by the resonance physics while the influence of …

We explore experimentally synchronization and persistent beating dynamics in coupled non-degenerate parametric oscillators. We demonstrate that synchronization is completely prevented due to mode competition, which is unique to non-degenerate oscillators.

Metalloregulators bind and respond to metal ions by regulating the transcription of metal homeostasis genes. Copper efflux regulator (CueR) is a copper‐responsive metalloregulator that is found in numerous Gram‐negative bacteria. Upon Cu(I) coordination, CueR initiates transcription by bending the bound DNA promoter regions facilitating interaction with RNA polymerase. The structure of Escherichia coli CueR in presence of DNA and metal ion has been reported using X‐ray crystallography and cryo‐EM, providing information about the mechanism of action. However, the specific role of copper in controlling this transcription mechanism remains elusive. Herein, we use room temperature electron paramagnetic resonance (EPR) experiments to follow allosterically driven dynamical changes in E. coli CueR induced by Cu(I) binding. We suggest that more than one Cu(I) ion binds per CueR monomer, leading to …

The TP53 gene is mutated in approximately 60% of all colorectal cancer (CRC) cases. Over 20% of all TP53-mutated CRC tumors carry missense mutations at position R175 or R273. Here we report that CRC tumors harboring R273 mutations are more prone to progress to metastatic disease, with decreased survival, than those with R175 mutations. We identify a distinct transcriptional signature orchestrated by p53R273H, implicating activation of oncogenic signaling pathways and predicting worse outcome. These features are shared also with the hotspot mutants p53R248Q and p53R248W. p53R273H selectively promotes rapid CRC cell spreading, migration, invasion and metastasis. The transcriptional output of p53R273H is associated with preferential binding to regulatory elements of R273 signature genes. Thus, different TP53 missense mutations contribute differently to cancer progression. Elucidation of the …