BINA

1975 articles

69 publishers

Join mailing list

Mar 2022 • Bulletin of the American Physical Society

Hidden magnetic memory and spontaneous superconducting vortices in alternating stacking compound 4Hb-TaS2

Eylon Persky, Anders Bjørlig, Irena Feldman, Avior Almoalem, Ehud Altman, Erez Berg, Itamar Kimchi, Jonathan Ruhman, Beena Kalisky

W61. 00009: Hidden magnetic memory and spontaneous superconducting vortices in alternating stacking compound 4Hb-TaS 2

Show more

Mar 2022 • arXiv preprint arXiv:2203.17133

Reduced Material Loss in Thin-film Lithium Niobate Waveguides

Amirhassan Shams-Ansari, Guanhao Huang, Lingyan He, Zihan Li, Jeffrey Holzgrafe, Marc Jankowski, Mikhail Churaev, Prashanta Kharel, Rebecca Cheng, Di Zhu, Neil Sinclair, Boris Desiatov, Mian Zhang, Tobias J Kippenberg, Marko Loncar


Mar 2022 • Langmuir

Mussel-Inspired Polynorepinephrine/MXene-Based Magnetic Nanohybrid for Electromagnetic Interference Shielding in X-Band and Strain-Sensing Performance

Sayan Ganguly, Poushali Das, Arka Saha, Malachi Noked, Aharon Gedanken, Shlomo Margel

The current work delivers preparation of MXene-based magnetic nanohybrid coating for flexible electronic applications. Herein, we report carbon dot-triggered photopolymerized polynorepinepherene (PNE)-coated MXene and iron oxide hybrid deposited on the cellulose microporous membrane via a vacuum-assisted filtration strategy. The surface morphologies have been monitored by scanning electron microscopy analysis, and the coating thickness was evaluated by the gallium-ion-based focused ion beam method. Coated membranes have been tested against uniaxial tensile stretching and assessed by their fracture edges in order to assure flexibility and mechanical strength. Strain sensors and electromagnetic interference (EMI) shielding have both been tested on the material because of its electrical conductivity. The bending strain sensitivity has been stringent because of their fast ‘rupture and reform …

Show more

Mar 2022 • Proc. of SPIE Vol

Nano logic gates based on gold nanoparticles-carbon dots hybrid and its FLIM imaging

Shweta Pawar, Hamootal Duadi, Yafit Fleger, Dror Fixler

In today’s research area it is extremely important to assemble nanomaterials into electric devices at the nanoscale level due to the rapid expansion of nanotechnology in various fields. Designing a nanohybrid composed of gold nanoparticles (AuNPs) and red-emitting carbon dots (CDs) can be used to develop a fluorescence lifetime imaging (FLIM) based logic gate that can respond to multiple input parameters. The AuNPs are conjugated to CDs surfaces through a strong covalent linkage between them. These fluorescence lifetimes-based logic gates could be the new way to overcome the limitation of fluorescence intensity-based logic gates. The Au-CDs nanohybrid shows significant fluorescence quenching of pristine CDs after conjugation of gold nanoparticles. This quenched fluorescence can be recovered back by using a proper recovering agent giving us a reversible logic output. This nanohybrid can be used …

Show more

Mar 2022 • International Journal of Molecular Sciences 23 (7), 3811, 2022

Behavioral Neuroscience in the Era of Genomics: Tools and Lessons for Analyzing High-Dimensional Datasets

Assa Bentzur, Shahar Alon, Galit Shohat-Ophir


Mar 2022 • Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XX …, 2022

Characterization of a large gated SPAD array for in vivo fluorescence lifetime imaging of drug target engagement

Jason T Smith, Alena Rudkouskaya, Shan Gao, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Shimon Weiss, Margarida Barroso, Xavier Intes, Xavier Michalet

Near-Infrared wide-field Fluorescence Lifetime Imaging (FLI) has become an increasingly popular method due to its unique specificity in sensing the cellular micro-environment and/or protein-protein interactions via FRET, but the approach is still challenging due to inefficient detection modules. Here, we report on the characterization of a large gated SPAD array, SwissSPAD2, towards in vivo preclinical imaging of FLI-FRET. Fluorescence decay fitting as well as phasor analysis are used to demonstrate the ability of SwissSPAD2 to accurately quantify short lifetimes and associated lifetime parameters in both in vitro and in vivo experiments, in full agreement with gated ICCD measurements.

Show more

Mar 2022 • High Contrast Metastructures XI, PC120110U, 2022

Chalcogenides for static and active meta-optics

Tomer Lewi, Danveer Singh, Sukanta Nandi, Shany Cohen, Pilkhaz Nanikashvili, Michal Poplinger, Doron Naveh

We present a study of various compositions of the chalcogenide family used for static and active metasurfaces. We start with large area CVD grown amorphous spherical Selenium nanoparticles on various substrates and show that their Mie-resonant response spans the entire mid-infrared (MIR) range. By coupling Se Mie-resonators to ENZ substrates we demonstrate an order of magnitude increase in quality factor. Next, we investigate topological insulators Bi2Se3 and Bi2Te3 metasurfaces. We study the optical constants of single crystal Bi2Te3 in the NIR to the MIR range, followed by fabrication and characterization of metasurface disk arrays. We show that these high permittivity metasurfaces can yield very large absorption resonances using deep subwavelength structures. Finally, we demonstrate ultra-wide dynamic tuning of PbTe meta-atoms and metasurfaces, utilizing the anomalously large thermo-optic …

Show more

Mar 2022 • Proc. of SPIE Vol

Identification of inhibitors for the S1-ACE2 interaction of the SARS-CoV-2 using magnetically modulated biosensors

Shira Roth, Amos Danielli, Michael Margulis

The outbreak of the coronavirus disease emphasized the need for fast and sensitive inhibitor screening tools for the identification of new drug candidates. In SARS-CoV-2, one of the initial steps in the infection cycle is the adherence of the receptor-binding domain (RBD) of the spike protein 1 (S1) to the host cell by binding to the angiotensin-converting enzyme 2 (ACE2) receptor. Therefore, inhibition of S1-ACE2 interaction may block the entry of the virus to the host cell, and thus may limit the spread of the virus in the body. We demonstrate a rapid and quantitative method for the detection and classification of different types of molecules as inhibitors or non-inhibitors of the S1-ACE2 interaction using magnetically modulated biosensors (MMB). In the MMB-based assay, magnetic beads are attached to the S1 protein and the ACE2 receptor is fluorescently labeled. Thus, only when the proteins interact, the fluorescent …

Show more

Mar 2022 • Langmuir

Mussel-Inspired Polynorepinephrine/MXene-Based Magnetic Nanohybrid for Electromagnetic Interference Shielding in X-Band and Strain-Sensing Performance

Sayan Ganguly, Poushali Das, Arka Saha, Malachi Noked, Aharon Gedanken, Shlomo Margel

The current work delivers preparation of MXene-based magnetic nanohybrid coating for flexible electronic applications. Herein, we report carbon dot-triggered photopolymerized polynorepinepherene (PNE)-coated MXene and iron oxide hybrid deposited on the cellulose microporous membrane via a vacuum-assisted filtration strategy. The surface morphologies have been monitored by scanning electron microscopy analysis, and the coating thickness was evaluated by the gallium-ion-based focused ion beam method. Coated membranes have been tested against uniaxial tensile stretching and assessed by their fracture edges in order to assure flexibility and mechanical strength. Strain sensors and electromagnetic interference (EMI) shielding have both been tested on the material because of its electrical conductivity. The bending strain sensitivity has been stringent because of their fast ‘rupture and reform …

Show more

Mar 2022 • ACS Applied Energy Materials

Combinatorial Synthesis and Screening of a Ternary NiFeCoOx Library for the Oxygen Evolution Reaction

A Usha Vijayakumar, N Aloni, V Thazhe Veettil, G Rahamim, SS Hardisty, M Zysler, S Tirosh, D Zitoun

The development of an efficient catalyst for the oxygen evolution reaction (OER) is critical to fulfilling the mission of hydrogen generation by water splitting. Various multicomponent systems have been investigated so far for the OER, although a systematic investigation is lacking and there are discrepancies as to which formulations make the best catalyst. Here, we perform a systematic investigation of a ternary Ni-Fe-Co oxide gradient library for the OER, using a combinatorial approach. This approach allows a much faster investigation of a vast compositional space compared to the traditional step by step approach. Also, it enables a more reliable comparison of the various catalysts as they all experience the same process and measurement conditions. We used the spray pyrolysis technique in combinatorial electrocatalyst screening for the first time for the generation of a gradient library of Ni-Fe-Co oxides …

Show more

Mar 2022 • ACS Energy Letters

Anion–Diluent Pairing for Stable High-Energy Li Metal Batteries

Chunnan Zhu, Chuangchao Sun, Ruhong Li, Suting Weng, Liwu Fan, Xuefeng Wang, Lixin Chen, Malachi Noked, Xiulin Fan

Rechargeable Li metal batteries (LMBs) have attracted wide attention as promising candidates for the next generation of energy-storage systems. However, limited Coulombic efficiency and unregulated dendrite growth restrict its application. Here, we report a kind of electrolyte by introducing fluorinated aromatic diluents into high-concentration electrolytes (HCEs). Unlike other localized HCEs, the fluorinated aromatic diluents pairing with anions promote the formation of a homogeneous and robust solid–electrolyte interphase (SEI), which endows Li metal with an ultrahigh Coulombic efficiency of ∼99.8%. The Li||LiNi0.8Co0.1Mn0.1O2 battery holds a capacity retention of >80% over 260 cycles even with a thin Li anode (20 μm) and a high cathode loading (3.5 mAh cm–2). A 1.8 Ah Li||NMC811 pouch cell with a lean electrolyte delivers an energy density of 340 Wh kg–1 and a stable cycling life over 200 cycles. The …

Show more

Mar 2022 • Langmuir

Mussel-Inspired Polynorepinephrine/MXene-Based Magnetic Nanohybrid for Electromagnetic Interference Shielding in X-Band and Strain-Sensing Performance

Sayan Ganguly, Poushali Das, Arka Saha, Malachi Noked, Aharon Gedanken, Shlomo Margel

The current work delivers preparation of MXene-based magnetic nanohybrid coating for flexible electronic applications. Herein, we report carbon dot-triggered photopolymerized polynorepinepherene (PNE)-coated MXene and iron oxide hybrid deposited on the cellulose microporous membrane via a vacuum-assisted filtration strategy. The surface morphologies have been monitored by scanning electron microscopy analysis, and the coating thickness was evaluated by the gallium-ion-based focused ion beam method. Coated membranes have been tested against uniaxial tensile stretching and assessed by their fracture edges in order to assure flexibility and mechanical strength. Strain sensors and electromagnetic interference (EMI) shielding have both been tested on the material because of its electrical conductivity. The bending strain sensitivity has been stringent because of their fast ‘rupture and reform …

Show more

Mar 2022 • International Journal of Molecular Sciences 23 (7), 3811, 2022

Behavioral Neuroscience in the Era of Genomics: Tools and Lessons for Analyzing High-Dimensional Datasets

Assa Bentzur, Shahar Alon, Galit Shohat-Ophir

Behavioral neuroscience underwent a technology-driven revolution with the emergence of machine-vision and machine-learning technologies. These technological advances facilitated the generation of high-resolution, high-throughput capture and analysis of complex behaviors. Therefore, behavioral neuroscience is becoming a data-rich field. While behavioral researchers use advanced computational tools to analyze the resulting datasets, the search for robust and standardized analysis tools is still ongoing. At the same time, the field of genomics exploded with a plethora of technologies which enabled the generation of massive datasets. This growth of genomics data drove the emergence of powerful computational approaches to analyze these data. Here, we discuss the composition of a large behavioral dataset, and the differences and similarities between behavioral and genomics data. We then give examples of genomics-related tools that might be of use for behavioral analysis and discuss concepts that might emerge when considering the two fields together.

Show more

Mar 2022 • Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XIX …, 2022

Golden exosomes: a new platform for cancer theranostics

Adi Anaki, Oshra Betzer, Menachem Motiei, Tamar Sadan, Dror Fixler, Rachela Popovtzer

Delivery of therapeutics to tumors is a major challenge, due to the sequence of formidable biological barriers in the body and tumor, which limit the penetration of various nano-carriers and drugs into the tumor. Exosomes are promising vectors for delivery of anti-tumor therapies, due to their biocompatibility, ability to evade clearance, and innate ability to home to, and interact with, target cells. However, promoting clinical application of exosome-based therapeutics requires elucidation of key issues, including exosome bio-distribution, tumor targeting, and the ability to overcome tumor barriers. Here, we examined these parameters using mesenchymal stem cell (MSCs)-derived exosomes loaded with gold nanoparticles (GNPs), aiming to delineate design principles for therapy loading and delivery. This novel technology provides essential and fundamental knowledge on exosomes for enhanced targeted drug …

Show more

Mar 2022 • ACS Energy Letters

Stabilizing High-Voltage Lithium-Ion Battery Cathodes Using Functional Coatings of 2D Tungsten Diselenide

Sandipan Maiti, Rajashree Konar, Hadar Sclar, Judith Grinblat, Michael Talianker, Maria Tkachev, Xiaohan Wu, Aleksandr Kondrakov, Gilbert Daniel Nessim, Doron Aurbach

Functional surface coatings were applied on high voltage spinel (LiNi0.5Mn1.5O4; LNMO) and Ni-rich (LiNi0.85Co0.1Mn0.05O2; NCM851005) NCM cathode materials using few-layered 2H tungsten diselenide (WSe2). Simple liquid-phase mixing with WSe2 in 2-propanol and low-temperature (130 °C) heat treatment in nitrogen flow dramatically improved electrochemical performance, including stable cycling, high-rate performance, and lower voltage hysteresis in Li coin cells at 30 and 55 °C. Significantly improved capacity retention at 30 °C [Q401/Q9 of 99% vs 38% for LNMO and Q322/Q23 of 64% vs 46% for NCM851005] indicated efficient functionality. TEM and XPS clarified the coating distribution and coordination with the cathode surface, while postcycling studies revealed its sustainability, enabling lower transition metal dissolution and minor morphological deformation/microcrack formation. A modified and …

Show more

Feb 2022 • Physical Review Applied

Visualizing Current in Superconducting Networks

X Wang, M Laav, I Volotsenko, A Frydman, B Kalisky

We present an experimental study of local magnetic imaging in order to visualize the current flow in superconducting networks. We track the evolution of the spatial distribution of the current flow as the network is driven from fully superconducting to fully normal phases. Our results highlight the factors that contribute to the disordered flow in superconducting networks during their collapse, and demonstrate that the current is never uniformly distributed in the network. These results can assist the design and development of circuits based on superconductors and Josephson junctions.

Show more

Feb 2022 • Physical Review Applied

Visualizing Current in Superconducting Networks

X Wang, M Laav, I Volotsenko, A Frydman, B Kalisky

We present an experimental study of local magnetic imaging in order to visualize the current flow in superconducting networks. We track the evolution of the spatial distribution of the current flow as the network is driven from fully superconducting to fully normal phases. Our results highlight the factors that contribute to the disordered flow in superconducting networks during their collapse, and demonstrate that the current is never uniformly distributed in the network. These results can assist the design and development of circuits based on superconductors and Josephson junctions.

Show more

Feb 2022 • Photonics

Signal-to-Noise Ratio Improvement for Multiple-Pinhole Imaging Using Supervised Encoder–Decoder Convolutional Neural Network Architecture

Eliezer Danan, Nadav Shabairou, Yossef Danan, Zeev Zalevsky

Digital image devices have been widely applied in many fields, such as individual recognition and remote sensing. The captured image is a degraded image from the latent observation, where the degradation processing is affected by some factors, such as lighting and noise corruption. Specifically, noise is generated in the processing of transmission and compression from the unknown latent observation. Thus, it is essential to use image denoising techniques to remove noise and recover the latent observation from the given degraded image. In this research, a supervised encoder–decoder convolution neural network was used to fix image distortion stemming from the limited accuracy of inverse filter methods (Wiener filter, Lucy–Richardson deconvolution, etc.). Particularly, we will correct image degradation that mainly stems from duplications arising from multiple-pinhole array imaging.

Show more

Feb 2022 • Biophysical Journal

Characterization of a large gated SPAD array for widefield NIR fluorescence lifetime imaging in vitro and in vivo

Jason T Smith, Alena Rudkouskaya, Shan Gao, Arin Ulku, Claudio Bruschini, Edoardo Charbon, Shimon Weiss, Margarida MR Barroso, Xavier Intes, Xavier Michalet

Optical imaging (OI) has become the most used alternative imaging tool for pre-clinical studies. Among all molecular imaging modalities, fluorescence optical imaging is central thanks to its high sensitivity, the numerous molecular probes available (either endogenous or exogenous) and its ability to simultaneously image multiple biomarkers or biological processes at various spatio-temporal scales. Especially, fluorescence lifetime imaging (FLI) has become an increasingly popular method, as it provides unique insights into the cellular micro-environment by non-invasively examining numerous intracellular parameters such as metabolic status, reactive oxygen species and intracellular pH. Moreover, FLI’s exploitation of native fluorescent signatures has been extensively investigated for enhanced diagnostic of numerous pathologies. However, to perform such measurements in intact, live specimen, it is required to …

Show more

Feb 2022 • Biophysical Journal

A novel single molecule fluorescence quenching technique for measuring distances below 3 nm

Benjamin Ambrose, Victoria E Hill, Robert A Shaw, Tristan Johnston-Wood, Matthew Willmott, Callum Johnston, Rebecca Mächtel, Thorben Cordes, Eitan Lerner, JG Hill, Shimon Weiss, Timothy D Craggs

Single-molecule FRET (smFRET) is a powerful biophysical tool for measuring intramolecular distances in biomolecules, however FRET is only effective over a 3-10nm scale. In this work we advance a quenching based method which uses Cy3B and Atto647N, a common dye pair used for smFRET. The quenching effect arising from this dye pair is sensitive to distance changes below 3nm, which is significantly lower than its R0 of 6.2 nm. It has previously been used to measure binary on/off transitions, such as local DNA melting in polymerase complexes. However, by using a series of DNAs labelled at various positions we have shown that we can quantitatively distinguish between slight changes in labelling separation. This quenching method is sufficiently sensitive to distinguish between DNAs labelled with dyes 1bp 3′ of each other from those labelled 5′ of each other. Additionally, this effect has been validated …

Show more

Feb 2022 • Biophysical Journal

Bacterial resting membrane potential: a case study with Bacillus subtilis

Debjit Roy, Xavier Michalet, Evan W Miller, Robert P Gunsalus, Robert T Clubb, Shimon Weiss

Bacterial membrane potential changes (Δψ) play an important role in bacterial metabolism and cellular processes as well as cell to cell communications in a biofilm. However, existing tools for reading Δψ quantitatively in individual bacterial cells as well as in bacterial communities are limited. A fluorescence lifetime imaging microscopy (FLIM) technique in combination with photo-induced electron transfer (PeT) based small molecule voltage sensitive dyes have been employed to quantify absolute resting membrane potential for individual Bacillus subtilis cells. The local electrostatic potential affects the relative extent of PeT in these dyes and thus alters fluorescence quantum yield (and hence fluorescence intensity as well as fluorescence lifetime). When localized into the bacterial cell membrane, the extent of PeT gets modulated by the resting membrane potential of the system. The suitability and voltage sensitivity of …

Show more

logo
Articali

Powered by Articali

TermsPrivacy